These mice may look like they’re modeling the Newcastle United 13/14 home shirt, but the truth is actually even more exciting, if a touch less adorable. Researchers from Columbia University Medical Centre have found that an enzyme-inhibiting drug can, in some cases, restore hair growth in mice with alopecia areata.
As the video below explains, the drug – which has already been cleared by the US Food and Drug Administration for the treatment of rheumatoid arthritis and blood diseases – inhibits the activity of Janus Kinase (JAK) enzymes, which are found in hair follicles. By limiting JAK activity, the mice started to grow their hair back in just ten days, and while the drug could be fed to the mice, rubbing it directly onto their skin showed even more lustrous growth.
Video of Blocking Enzymes in Hair Follicles Promotes Hair Growth
After three weeks, the mice were back to their old, furry selves, and while this doesn’t necessarily mean it’ll be the baldness cure that humans are constantly seeking, it could be a strong start. And potentially not just for male and female pattern baldness, but for hair loss due to chemotherapy.Continue reading